In Memory of Prof. Amir Lerman | gistmd

Labor Induction Navigating the journey of childbirth can be both exciting and challenging. To support and empower expecting mothers through this unique phase, GistMD presents its ‘Personalized Labor Induction Education Program’. Through this innovative platform, we aim to demystify the labor induction process and to prepare women for what to expect. This leverages the power of digital health and offers a personalized, engaging, and empowering learning experience. Benefits Improves patient preparation Increases patient satisfaction How It Works The clinic sends the patient a link to her mobile phone Patient fills out a personalization questionnaire 4 Based on the the answers to the questionnaire, the system automatically creates a personalized animated video and screens it to the patient Patients are encouraged to download, read and print a personalized informed consent form 1 2 3 ״Providing a pregnant woman with organized information through a video, illustrating what she can expect during the birthing process, leads to fewer surprises and greatly facilitates the entire experience. This approach not only assists us the midwifes, but also reduces the need for extensive explanations from doctors.״ ״If I was a pregnant woman with limited knowledge, being provided with a video explaining what an epidural entails would have greatly boosted my sense of preparedness, confidence, and understanding. It exemplifies the potency of knowledge, which effectively reduces feelings of fear, anxiety, and uncertainty.”

Discharge Post-discharge is one of the most challenging phases in a patient's healthcare journey. The Gistmd’s Discharge Education Module engages patients to continue their treatment at home and effectively manage their recovery. The module helps patients to better understand the post-discharge demands, step by step. Using the personalized video and a user-friendly interface, the program guides patients in grasping the importance of maintaining follow-ups with their family doctor, undergoing follow-up tests, and staying consistent with their new prescribed medications. How it works Effortless Gui dance Follow-ups Our intelligent engagement system simplifies the task of monitoring the patient’s follow-up care The easy and simple method to create a personalized post-discharge intervention The method must be simple, yet comprehensive, considering individual patient factors like clinical condition, demographics, and personal preferences Tailor-Made Education Module: A Personalized Pathway to Empowerment In the complex world of healthcare, one size does not fit all. Every patient's journey is influenced not only by unique demographic and clinical characteristics but also by expected outcomes Let’s gist! The most important information for the patient is in the palm of his hand Recovery doesn't end at discharge, and neither does our commitment. Gistmd’s Discharge Education Module is designed with empathy, innovation, and a patient-centered approach

Meet Our Team Gist’s executive team has extensive experience leading private and public health-tech companies with a strong focus on personalized medicine. The team is supported by a multidisciplinary group of top experts in medicine, artificial intelligence and machine learning, health policy, animation and visual communication, anthropology, and psychology. Executive Leadership Dan Rolls Founder & CEO Dan is a serial entrepreneur driven by a passion for developing digital health products, with a focus on patient engagement and improving the care experience. Aurelia Setton Co-founder & Chief Medical Officer Director, Internal Medicine, Tel Aviv Medical Center and founder of leading BioTech compaines. BenAmi Goldenberg Co-founder & Chief Technology Officer Tech entrepreneur and AI innovator with 20+ years of experience in software engineering, product strategy, and startup leadership. Orit Rozenblum VP, Operations Orit brings over 20 years of experience building sales and operations for startups and holds an MBA from MIT Sloan. She leads revenue growth and strategic partnerships at GistMD. Prof. Ori Rogowski Co-founder & Chief Medical Officer Director, Internal Medicine, Tel Aviv Medical Center. Elinor Karni VP, Product & Design With over 20 years of expertise in developing digital identities, products, and creating unique digital experiences, Elinor leads product design at GistMD. Ronen Zhurat Head of Production Experienced Owner with a demonstrated history of working in the animation industry. Daniella Benaim Head of Communications & Community Daniella leads GistMD's social media presence and communication strategy, fostering community engagement and supporting our mission. Board & Strategic Advisory Dr. Ilan Cohn Co-founder & Chairman of the Board Dr. Cohn leverages his extensive experience in founding and developing healthcare companies and building intellectual property assets to guide GistMD's innovation and strategic growth. Zvi Zahavi, MD Board Member & Strategic Advisor, Digital Health Dr. Zahavi brings extensive experience in digital health entrepreneurship, improving communication between caregivers, healthcare organizations, and market expansion. Prof. Ian Gralnek Chief Medical Advisor – GI Clinical Strategy & Market Development Professor Gralnek, a globally recognized GI authority and past-President of the ESGE, brings over 350 peer-reviewed works to lead our evidence-based clinical strategy and market expansion. Medical Advisory Board Prof. Idit Matot Chief Medical Advisor – Anesthesiology A President of the European Society of Anesthesiology & Intensive Care, she brings extensive expertise and leadership to the forefront of the anesthesiology and intensive care across Europe. Dr. Alan Epstein Executive Medical Advisor – Gastroenterology Former GI Director at Roger Williams Medical Center, leading clinical innovation and research excellence in digestive health. Prof. Shmuel Banai Chief Medical Advisor – Cardiology Director, Cardiology Division, Tel Aviv Medical Center. Prof. Anat Loewenstein Chief Medical Advisor – Ophthalmology Director, Ophthalmology Department, Tel Aviv Medical Center; President, Israel Ophthalmology Society; World-Renowned Ophthalmologist. Prof. Zvi Grunwald Strategic Advisor, Perioperative Care The James D. Wentzler Professor and emeritus chair of anesthesiology at Sidney Kimmel Medical College. Thomas Jefferson University. Prof. Yariv Yogev Chief Medical Advisor – Obstetrics & Gynecology Director, Lis Maternity and Women's Hospital, Tel Aviv Medical Center. Prof. Zaza Iakobishvili Chief Medical Advisor – Cardiovascular Medicine Tech entrepreneur and AI innovator with 20+ years of experience in software engineering, product strategy, and startup leadership. Orit Neudorfer, MD Medical Advisor & Head of Research Medical Advisor & Head of Research Prof. Maayan Konigstein Medical Advisor – Interventional Cardiology Head of the cardiac, Tel Aviv Medical Center Prof. Ofer Havakuk Medical Advisor – Heart Failure & Cardiology Prof. Havakuk leads development of GistMD’s heart failure program Bat Zion Shachar, MD Chief Medical Advisor – Cardiovascular Medicine Attending, Gynecology and Obstetrics, Maccabi Healthcare Services Isaac Brzezinski Sinai, MD Medical Advisor & Head of Research Anesthesia Department Resident, Tel Aviv Medical Center Human-Centric Design Advisors Demetria Bolden, PhD Advisor, Health Equity & Inclusion Dr. Bolden leverages her expertise in health equity research to enhance patient empowerment by addressing disparities in healthcare access and outcomes. Daniel Nave, PhD Advisor, Medical Anthropology & Patient Consciousness Daniel enhances engagement strategies by incorporating cultural insights and an appreciation for patient consciousness. Nehama Karpol Burak Advisor, Patient Psychology & Behavioral Health Nehama enhances patient engagement through her expertise in human behavior, emotions, providing personalized and empathetic care.

The Toolbox is an app providing medical staff with highly convenient access to personalized educational modules for common inpatient settings: Colonoscopy, Cardiac Catheterization, Gastroscopy, Heart Failure, Nasogastric Tube, Pleural Tap, and Urinary Catheterization. After selecting the required module, the caregiver uses a simple interface to personalize the video -- by gender, age, language preference, and relevant background condition(s) -– and share it with the patient using a variety of methods: email, SMS, WhatsApp, or scannable QR code. Inpatient Education Toolbox Play Video Facebook Twitter Pinterest Tumblr Copy Link Link Copied Now Playing Plural Tap Showreel English 00:41 Play Video Now Playing Cardiac Catheterization 00:39 Play Video Now Playing Urinary Catheter 00:44 Play Video Now Playing colonoscopy preparation 00:43 Play Video Cross Device Functionality The app is available in a variety of subscription models, and provides the caregiver with the same user experience on any device -- smartphone, tablet or desktop computer.

Preanesthesia Patient Education Kit Benefits + Effective pre-procedure guidance, accurate calibration of expectations, and increased patient satisfaction + Improved patient engagement and safety through use of personalized tools + Reduction in preanesthesia evaluations The Adult Preanesthesia Patient Education Kit was designed and developed by a multidisciplinary team of senior physicians in the fields of anesthesiology, intensive care and pain. Patient engagement is personalized based on information entered by the surgery coordinator and by the patient, who fill out a preoperative questionnaire. Patients whose background condition does not justify a pre-anesthesia evaluation and have viewed a personalized video, are exempted from a pre-anesthesia evaluation. + + + How it works 1 After a decision on a procedure is made, the surgery coordinator opens a new event on the platform 2 Patient receives text message from hospital with link to video and preoperative questionnaire 3 Patient fill out questionnaire 4 Patient views personalized video 5 Patient affirms receipt and understanding of preoperative instructions The patient is presented with questions equivalent to points regarding medical background, lifestyle, functional abilities and more Patients' responses to preoperative questionnaire enable hospital anesthesiology team to pre-screen for necessity of a preanesthesia evaluation Scoring System The patient must come to a preliminary meeting with an anesthesiologist. Exemption from a preliminary appointment and will meet the anesthesiologist only on the day of surgery 2 points or more less than 2 points Request Demo

Fall Prevention Program With the impact of personalized animated videos, the ‘GistMD Hospital Fall Prevention Program’ engages patients and healthcare professionals in effective ways to prevent falls. By bridging information gaps and embracing cultural sensitivity, the program ensures health equity and health literacy. Through an interactive and multilingual platform, the program delivers personalized risk assessments, and empathy-driven education for patients and caregivers, to improve safety and patient engagement. How it works GistMD's ‘Hospital Fall Prevention Program’ begins with a comprehensive assessment to pinpoint an individual's specific fall risk factors. The program delivers culturally sensitive, personalized animated video education, in multiple languages tailored to these identified risks. The program provides a robust monitoring system, capturing real-time data on patient education and activation at both departmental and hospital-wide levels for efficient program evaluation and improvement.

Intravitreal Injections Using a personalized animated video, the Intravitreal Injections Education Module effectively engages patients and encourages them to begin and complete their treatment course. In addition to bridging anxiety-inducing information gaps and providing personalized preparatory instructions, the Module taps into the power of empathy to improve engagement using a personalized simulation of the vision-affecting symptoms experienced by the patient. Click on the images to to see how the video is personalized to the patient's condition Demonstrating empathy by simulating the patient's symptoms Retinal Vein Occlusion RVO AMD Age Related Macular Degeneration DME Diabetes Related Macular Edema System benefits Improves patient preparation Reduces medical and administrative staff workloads Bridges crucial information gaps Patient journey Patient Clinic Unengaged patients receive reminders 96 and 48 hours ahead of procedure The platform monitors patient engagement and sends reminders to unengaged patients 96 and 48 hours ahead of procedure. Patients unresponsive to their last reminder are flagged for direct intervention by clinic staff (see below). Clinic staff open a new patient case and update the patient’s personal information (age, gender, and language preference), the indication for treatment (RVO, AMD, or DME), the date and time of the procedure, and the patient’s mobile phone number. Optionally, the clinic’s patient management system can be connected directly to the platform. New patient case opened by clinic 1/4 Patients and/or caregivers receive an SMS with link to personalized animated video Patients and/or caregivers receive an SMS to their mobile phone with a link to a personalized animated video and personalized preparatory instructions. video 1/3 An easy-to-use administration module monitors patient engagement. Unengaged patients are flagged for direct intervention by staff. The module provides reports in a number of formats. Administration module monitors patient engagement 1/1 Case Manager 2.O Digitized informed consent form Patients are encouraged to read the personalized informed consent form they will sign in the presence of a physician at the clinic. After watching the video, the patient can view, download and print personalized preparatory instructions. Personalized preparatory instructions "I've been treated with intravitreal injections for two years now. I watched the video and it’s simply amazing! I identified with the character and her symptoms, and I really liked that the video explained how the substance works in the eye. After watching it, I suddenly understood the treatment and what happens inside my eye." Patient, 58 “I truly appreciated the clear and lighthearted manner in which the instructions were presented. Despite having undergone multiple injections in the past year, the video still provided valuable assistance. It's wonderful to receive such a pleasant video on my phone, addressing me directly." Patient, 76

The patient-centered care approach -- which focuses on the unique characteristics and needs of each patient, rather than the disease -- has been adopted by healthcare systems worldwide. Yet communication gaps -- linguistic, cultural, and informational -- between patients and their care providers have made practical implementation difficult. This exhibition, launched on March 30 2022 and entitled The Art of Engagement , presents a groundbreaking Israeli solution for bridging these gaps: animated educational kits personalized for each patient. The kits are in various stages of implementation across the Israeli healthcare system, and are sparking a tangible revolution in patient experience. Four of them were devoted to select product areas, Ophthalmology, Cardiology, Anesthesia, and Obstetrics, with one showcasing our creative and technical processes. The exhibition featured five main displays Artist studio The Artist’s Studio display provided a window into the knowhow behind our products. It walked visitors through the entire production process: script, storyboard, character design, background design, and scene animation. Each stage was demonstrated in augmented reality (AR), which visitors experienced using their smartphones. At the end of the tour visitors were invited to put together their own personalized video using a demo administration module displayed on a large touchscreen. I don’t care about GistMD’s sales. That’s not what I care about. What I care about is that every patient with fecal occult blood does a colonoscopy. That’s what I care about. [I care] that every patient with a positive pap smear does a colposcopy. Because I know what happens to those who don’t. Prof. Ronni Gamzu, CEO of the Tel Aviv Medical Center (Ichilov)

The GistMD Solution for Pre-Anesthesia Education for Children Deployed at Tel Aviv Sourasky Medical Center in 2020 Benefits + Effective pre-procedure guidance, accurate calibration of expectations, and increased patient satisfaction + Improved patient engagement and safety through use of personalized tools + 50% reduction in pre-anesthesia evaluations How the product was used to reduce 50% of pre-anesthesia evaluations Product designed and developed by a multidisciplinary team of senior physicians in the fields of anesthesiology, intensive care, and pain. Patient's animation is personalized based on information entered by the surgery coordinator and by the patient's parents, who fill out a preoperative questionnaire. Patients whose background condition does not justify a pre-anesthesia evaluation and have viewed a personalized video, are exempted from a traditional pre-anesthesia evaluation. How it works After a decision on a procedure is made, the surgery coordinator opens a new event on the platform 1 2 Parents of patients receive a text message from hospital with link to video and preoperative questionnaire 3 Parents fill out questionnaire 4 Parents and patient view personalized video 5 Parents affirm receipt and understanding of preoperative instructions Parents responses to preoperative questionnaire enable hospital anesthesiology team to pre-screen for necessity of preanesthesia evaluation 1 2 10 1 1/10 If parents entered negative responses to all questions, and viewed the video, no further evaluation is required, and the patient arrives at the hospital on the day of the surgery, meeting the anesthesiologist at the operating room. If parents did not respond to the questionnaire, or entered one or more positive responses, a separate pre-anesthesia evaluation at the hospital is scheduled for the patient. No Yes "The instructions were clear, and I understood the steps. My daughter hasn't had surgery before. Knowing that she might act differently after the surgery was reassuring because it's normal after anesthesia. If I didn't know this, I would have been very anxious" Mother of the pateint "The video was both pleasant and informative, clearly explaining the process and soothing my nerves. As someone who prefers to have a comprehensive understanding, it was reassuring to know everything in advance. It was user-friendly and the reassuring tone made it less intimidating." Patient, 8 Request Demo

Change a stoma bag Stoma - Care Principles Explore GistMD's Stoma Care Principles Guidance System, encompasses empowerment, support, and patient engagement. Our personalized education equips individuals for effective stoma management, enabling them to better adapt to their new medical condition. Tailored materials empower patients to confidently manage their stoma care, promoting self-sufficiency in managing their condition. Patient education regarding stoma’s care principles can pose challenges to the medical staff but GistMD's platform is here to assist them! Using comprehensive and accessible information, our platform empowers patients to proactively manage their care. This not only reduces the patient’s need for guidance but also saves valuable time for medical staff. What is Stoma? Patient journey Patient Clinic Receiving a text message and choosing Personal Avatar GistMD helps patients adapt smoothly to life with stoma, at home as part of their daily routine. We offer important insights, helping patients recognize the red flags and better understand what is considered an emergency, and demands consulting with specialized stoma nurses. Stoma Care in daily routine Patients receive a text with a link for instant access to our web platform - no downloads needed. The patients can customize their experience by choosing an avatar that reflects their identity better: gender, age, and ethnicity. This personalized character will appear in the educational videos, making learning both informative and relatable. Monitoring patient engagement Our platform actively monitors compliance data and engagement by tracking patient actions such as link access, questionnaire completion, and video views. This valuable data equips clinicians to offer targeted support to those facing challenges with the guidance system. Moreover, the platform can send reminders to unresponsive patients, ensuring they remain dedicated to their stoma care treatment. Personalized Stoma Care Principles Guidance The nurse creates cases for new patients, considering the patient’s individual stoma type and needs. Personalized educational videos are tailored accordingly. Integrating our platform with the division's management system adds convenience for healthcare staff. Creating a new case Artboard 1 stoma-gallry-2-heb Artboard 1 1/2 GistMD offers personalized stoma care guidance, empowering patients well - being by providing them a sense of control and self-sufficiency. We provide them with practical instructions for managing stoma care, including information about their specific equipment. From dietary guidelines to intimate relationships, we address physical changes and provide guidance for a more empowered living. Our aim is to ensure that patients are well-informed in their journey adapting to lifestyle changes.

The Gist Notebook helps physicians communicate diagnoses using an animated heart simulator personalized to each patient’s pathology, symptoms, and proposed tests. Development of the app was led by Professor Shmuel Banai, Director of the Cardiology Division at the Tel Aviv Sourasky Medical Center, and Dr. Ofer Havakuk, Director of Cardiologic Hospitalization at the hospital. The Gist Notebook app At the core of the app is an animated heart simulator that the physician easily personalizes to the patient's individual pathology, producing a vivid animated simulation on the device. The simulation can then be shown to the patient at the clinic, as a communications aid during consultations. An animated heart simulator Personalize a live interactive heart Select your patient’s pathology, symptoms, and treatment… …to create a personalized video Share the video with your patient Document and archive patient education Personalize a live interactive heart Select your patient’s pathology, symptoms, and treatment… …to create a personalized video Share the video with your patient Document and archive patient education Personalize a live interactive heart Select your patient’s pathology, symptoms, and treatment… …to create a personalized video Share the video with your patient Document and archive patient education Personalize a live interactive heart Select your patient’s pathology, symptoms, and treatment… …to create a personalized video Share the video with your patient Document and archive patient education Personalize a live interactive heart Select your patient’s pathology, symptoms, and treatment… …to create a personalized video Share the video with your patient Document and archive patient education Personalize a live interactive heart Select your patient’s pathology, symptoms, and treatment… …to create a personalized video Share the video with your patient Document and archive patient education Empower your patients Further personalization -- of symptoms, proposed tests, and the patient’s gender and language -- enables creation of a 3 minute long personalized educational video. The video, accompanied by a personalized message, is shared with the patient by SMS, Whatsapp or email, and can be reshared with family.